How is Aperiomics Different?

Aperiomics is the ONLY company identifying EVERY known pathogen in ONE test.  No other company in the world is offering healthcare providers this type of service.  Period.  Our mission is simple: change everything about how infections are identified. Aperiomics’ goal is to help sick patients find answers.  We do this by taking advantage of the newest technologies.  Aperiomics identifies all known bacteria, viruses, fungi and parasites that have been genetically sequenced.  Aperiomics gives healthcare providers access to the most powerful tool in identifying the cause of infection.  Healthcare providers can then give patients a clear path to healing.

How is this Possible?

Aperiomics uses a technology called deep shot-gun metagenomic sequencing.  This sequencing creates a genetic fingerprint of every living creature in clinical samples.  Once a sample is sequenced, we remove the human DNA from this terabyte-sized file to focus on non-human DNA.  We then run the remaining sequence data through our software and against the Aperiomics Microbial Database™, the world’s largest, most complete database of pathogens.  So instead of labs that can test for one or a handful of pathogens at a time, Aperiomics can test 37,000+ microorganisms at once!

Not all “Next-Generation Sequencing” is the Same

Although the deep shot-gun metagenomic sequencing technology Aperiomics uses falls under the umbrella of “next-generation sequencing” (NGS), it’s very different than other “NGS” technologies being used in the lab testing market today.

The most commonly used “NGS” technology used by clinical labs is called 16S sequencing.  16S sequencing is similar to PCR testing in that it creates many copies of small genetic fragments.  These copies are then compared to a limited database of the 16S gene to identify the bacteria present.  By comparison, deep shot-gun metagenomic sequencing utilizes 100% of the DNA vs .001% of the DNA with 16S – 100,000 times more information than 16S and thus more robust results.  16S sequencing can identify thousands of bacteria to the genus level, but is unable to identify virus, fungi, or parasites.   The end result is at best, the “Cliff Notes” version of what Aperiomics does.

For more information, visit www.aperiomics.com